The Archive · 1940

Bring Greatest Engine Efficiency

Throughout your car's life, Champions will keep the up to its best power, sp and economy—ready to serve pions provide the strong hot sparks that ensure fuller combustion of the fuel. sources could be put to work for the defence of our cause, stated Mr.

Champions save you money! especially of chemistry, is not to be counted on.

The prize-winner whose work is of the widest public interest is Professor Gerhard Dimagk, of the Bayer Company at Elberfeld. He is the discoverer of Prontbsil, the first of the new drugs which are the most remarkable medical discovery of the last decades. Domagk's results are due to an extension of the method developed by the great Jewish chemist Paul Ehrlich. If certain dyes are introduced into living tissues they are absorbed differently by various parts of the tissues. Some parts are picked out and stained brightly, while others are unaffected. Ehrlich had the idea of finding dyes which would pick out bacteria only. He then attached poisonous arsenic atoms to the dyes in the hope that this would kill the bacteria. He failed in this attack on bacteria, but was rewarded by the tremendous discovery of salvarsan, which would kill the organism that produces syphilis. After Ehrlich's researches it was assumed that bacteria could not be successfully attacked by his method. Ehrlich had supposed that if a dye was to be effective inside the body it must be a disinpectant outside it, like salvarsan, which contains arsenic.

Domagk started a new series of experiments some years aso, in which he discarded this assumption. He tried the effects of a series of dyes on bacteria in the body, irrespective of their effects on bacteria Outside the body. He published the discovery of Prontosi in 1935. This is astonishingly effective against streptococcal infections, such as puerperal fever and gonorrhea. Trefouel, Nitti, and Bovet in France have found that a simpler component of Pronto-sil, named sulphanilamide, has similar properties, and a variant has been produced in England, M. and B. 693, which is remarkably effective against pneumonia,

Text read from the printed page and cleaned; old type leaves the occasional error.

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